With a five times greater chance for women to be diagnosed over men, Hypercortisolism or Cushings ailment occurs in an estimated trip the light fantastic biscuit to 15 million people per year amid the ages of twenty dollar bill to fifty (Cushings Disease). Out of those ten to fifteen million people astir(predicate) ten percent of those cases be children (Keil). Discovered by Dr. Harvey Cushing in 1932, this disease is caused by an over outturn of the hormone ACTH in the pituitary gland gland fixed behind the optic nerves, at the base of the whiz. This overproduction produces a tumor on the pituitary gland, which can cause a smorgasbord of symptoms for the patient. These symptoms can drastically change the patients mood and appearance (Margulies) In 1912, Dr. Harvey Williams Cushing was born in Cleveland, Ohio and was ameliorate through Johns Hopkins, Yale and Harvard Universities. He was neurosurgeon and taught medicine at Harvard from 1912 to 1932, when he t hen became a prof at Yale. His specialty was the brain and the pituitary gland. Patients were sent to Cushing from over and by 1931, he had performed more(prenominal) than 2000 tumor operations (Brennan and Clarage). Cushing disease is the reach given to a specific type of Cushings syndrome caused by too a good deal ACTH production in the pituitary gland.
The tumor, or adenoma, secretes enlarged amounts of ACTH which causes the suprarenal gland glands to overproduce the steroid called cortisol. This disease was draw by Harvey Cushing in 1932. It is as well called Itsenko-Cushing Syndrome, hyperadrenocorticis m or hypercortisolism. Cushings can also b! e found in dogs, horses and sometimes, still rarely, in cats (Feldman and Gilkers). in that respect are a wide variety of both somatogenic and emotional symptoms for the disease. Some of the physical symptoms entangle; upper luggage compartment obesity with thin arms/legs, a round, red effective typeface or moon face. More admit; slower growth in children, devoted to acne or another(prenominal) skin infections, stretch marks (also called straie), thinning...If you deprivation to get a full essay, order it on our website: OrderCustomPaper.com
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