Case study Essay Example | Topics and Well Written Essays - 1000 words - 29

Case study - Essay Example Human genome is responsible for carrying hereditary information. In human, the structure is known as deoxyribonucleic acid (DNA). The structure carries all the human genes. There are four chemical bases found in the DNA (EDinformatics 1999). They include adenine (A), thymine (T), cytosine (C), and guanine (G) (EDinformatics 1999). Covalent bonds of phosphodiester join the bases together (Makalowski 2001). The bond helps in alignment of bases in specific pairs. Moreover, the structure exhibits a double helical organization. The organization is because of hydrogen bonding between the base pairs (EDinformatics 1999). The hydrogen bond helps in linkage of one complementary strand to the other (EDinformatics 1999). In human, the human genome is stored on 23 pair’s chromosomes (EDinformatics 1999). In these pairs, 22 are autosomal chromosome pairs while the rest is involved in determining sex (EDinformatics 1999). In human, there is a way in which genes are arranged in a genome. For example, they may be in the same (tail to the head) or opposite orientation (head to the head or tail to tail) (Makalowski 2001). The majority of human genomes account for non-exonic sequences (Makalowski 2001). However, a number of genes occupy the same genomic space. In addition, there is a tremendous difference in the human genome. Scientists have shown the difference to be occurring in millions of locations. In these locations, the single base DNA differences (SNPs) takes place in human (EDinformatics 1999). The resulting variation has led to exploitation by various researchers on the use in health screening. On the other hand, there has been interest in human mitochondrial genome (EDinformatics 1999). The genome has been shown to play a significant role in mitochondrial diseases (EDinformatics 1999). The understanding of genetic variation has an immense implication on the field of medicine. In fact, it has generated a vast potential in understanding and promoting