Running Head : GENES AND THE ENVIRONMENTOn the Interaction of Genes and Environment in get hook cadre anemiaOn the Interaction of Genes and Environment in reaping hook Cell AnemiaSickle prison mobile phone anaemia is a componenttic parentage dis which affects haemoglobin the protein carried by red blood booths and trustworthy for carrying oxygen passim the corpse ( redbreast , 2007 . The inheritance course for the dis is autosomal recessionary in that the person needs to be homozygous for the reap hook cell allele in for it to unvarnished (Krogh , 2005Sickle cell anemia affects peck globally although it occurs more often in people of plastered ethnicities . For instance , 70 000 to 80 000 Americans as parentage to deuce million people of African descent (Robin , 2007 ) are change by the illnessAlthough the relat ive frequency of sickle cell trait in Africa was thrice as a good deal to that in America the disease itself was much less third estate . Various hypotheses have been proposed in to account for this discrepancy much(prenominal) as better wellness of the adult African universe of discourse senior higher African child mortality rate as well as peril healthy thoughtions in the unite States . A finding during the primeval 1950s however has take to the definitive cause bottom the difference : the huge shock of the environment on genes in sickle cell anemiaAnthony Allison , determined by the results found by E . A . beet in North Rhodesia in 1946 , studied the interaction among sickle cell anemia and malaria . He found that the frequency distribution of the sickle cell condition mapped very nearly to that of the most severe forms of malaria (Natural Sciences tuition Center , 2003 . Using the concept of balanced polymorphism , he explained the results he achieved . He thi nk out that heterozygous individuals for hem! oglobin S had better chances of combating the effectuate of malaria over those who had normal hemoglobin As such , the evil effect of homozygosity in the recessive gene is offset and the high prevalence of the recessive gene in the population is maintainedIt is thus constructive to note that not all mutations are disadvantages .
In most cases , the environment compensates and makes them plus and necessaryReferencesKrogh , David (2005 . Biology : A transport to the Natural World , third Edition . New island of Jersey : Prentice - Hall , IncMiller , Robin (2007 . Sickle CellAnemia . Nemours Foundation identify Re trieved celestial latitude 15 , 2007 , from HYPERLINK hypertext transfer protocol / cyberspace .kidshealth .org /teen /diseases_conditions / ancestral /sickle_cell_ anemia .html http /network .kidshealth .org /teen /diseases_conditions /genetic /sickle_cell_a nemia .htmlNatural Sciences Learning Center (2003 . Biogeography and Ecology of Sickle Cell Anemia . Washington University - Biology Site . Retrieved December 15 , 2007 from HYPERLINK http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html anomalous sickle shaped red blood cells , as contrast to their normal disc -shaped appearance is the sensual manifestation of the dis and results to the cells d which is responsible for carrying oxygen throughout the body . It is recessive in that the person needs to be homozygous for the sickle cell allele for the dis...If you want to get a full essay, instal it on our website: OrderCustomPaper.com
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